Cleansing protocols after water drugs – Articles


Again and again we grow to be stunned once we see the contents that pop out of the pipes once we empty them out for the primary time. This “symbol” corresponds to the residues of medicines, dissolved salts and different solids carried within the water that precipitate and increase within the pipes. Dorr et al. (2009) concluded that:


  • The soluble elements react amongst themselves blockading the medicine techniques.
  • The use of pH modifiers impacts the water-soluble antibacterial drug answer.


Figure 1. Solutions and precipitation products that can block the medication system. A: Crystals and black mud B: Crystals and floating precipitate; C: White precipitate in a solution; D: Floating precipitate. Source: Dorr PM, Madson M, Wayne S, et al. (2009).
Determine 1. Answers and precipitation merchandise that may block the medicine gadget. A: Crystals and black dust B: Crystals and floating precipitate; C: White precipitate in an answer; D: Floating precipitate. Supply: Dorr PM, Madson M, Wayne S, et al. (2009).

Those conclusions display the significance of cleansing the water drugs techniques after the remedies, and the limitations we will have to believe when blending therapeutical compounds that may compromise the sanitary-productive building of the pigs.


Desk 1. Soluble medication blending (pairings) and observations all through 24 hours. Supply: Dorr PM, Madson M, Wayne S, et al. (2009).

















+ Precipitate – No precipitate
Tetracycline Oxitetracycline Clortetracycline Clortetracycline Sulfamethazine Sulfamethazine Tiamulin
Acetylsalicylic acid + + + +
Sodium salicylate + +
Amoxicillin +
Trimetroprim Sulfamethoxazole + + +
Penicillin G potassium + + + +
Neomycin 1 +
Neomycin 2 +
Tetracycline +
Oxitetracycline +
Clortetracycline +
Clortetracycline Sulfamethazine +


All through the emptying of the construction for its cleansing and disinfection earlier than any other batch of pigs is offered, and when medicating the water, we will be able to must keep an eye on the vital issues of the gadget with the intention to take care of the biosecurity of this nutrient within the farm. Aside from the drinkability of the water, we will have to keep an eye on 4 fundamental issues:


  1. Steady provide
  2. True consumption
  3. Blank and disinfected pipes
  4. Design and upkeep of the installations


A proper protocol permits the installations to be maintained in a really perfect state for his or her use, at the side of retaining them blank and disinfected.


1. The set up:


The objective is to keep an eye on the vital issues within the installations:

Figure 2. Critical points in the installations.
Determine 2. Essential issues within the installations.


2. Cleansing:


The design of the tanks and the pipes will have to permit for its entire drainage.


2.1. Tank:


  • Higher lid for combating the access of dust.
  • Clear out on the access level with the intention to keep away from sedimentations.
  • Decrease drain with the intention to facilitate the emptying.
  • Versatile pipe with the intention to ensure that water access during the higher house and to scale back the opportunity of the access of dust.
  • Stage keep an eye on (water-level buoy).
  • Slope smaller than 1:20.


Figure 3. Steps in cleaning the water tank.
Determine 3. Steps in cleansing the water tank.

2.2. Pipes:

  • Shut the access coming from the overall tank.
  • Draining or “flushing” at a top force thru every pipe till the water comes out totally blank. We’d like a “by way of move” so the filter out does now not scale back the force.
  • If dust could be very glaring, we will be able to must flood the pipes with a cleaning-descaling answer. This answer will have to stay all through the time beneficial by way of the producer (12- 24 h) so it might probably do its task.
  • Draining and rinsing. Check the absence of cleansing answer residues.
  • Open the ingesting water influent of the overall tank.


The filter out is an very important component for keeping up the pipes gadget blank.


Test the filters


  • They will have to save you the access of sunshine to keep away from the expansion of algae.
  • The usage of filters with disposable cartridges isn’t beneficial (there may be the danger of working out of spare cartridges or shares).
  • The cleansing of the filters must be performed when essential (relying at the high quality of the water and the frequency of the medicines).


Figure 4. The filter is an essential element for maintaining the pipes system clean.
Determine 4. The filter out is an very important component for keeping up the pipes gadget blank.

We will have to test that the go with the flow is proper in all of the pipes:


Cleansing the pipes and checking the go with the flow

Figure 5. Draining the pipes and checking the water flow.
Determine 5. Draining the pipes and checking the water go with the flow.


Graph 2. Water supply per pen as a function of room length. Source: Almond G. and Monahan (2000).
Graph 2. Water provide consistent with pen as a serve as of room duration. Supply: Almond G. and Monahan (2000).

Assessment the usage of “descalers” or acid-based merchandise within the case that the take a look at presentations quite a lot of minerals (Ca, Mg and Mn) that purpose scales.


3. Disinfection


3.1. The sanitizer:


So as to make a choice one we will have to be mindful:


  1. The bactericide spectrum.
  2. Neutrality towards the physical-chemical adjustments of the water (particularly pH).
  3. Efficacy towards the biofilm.


The Royal Decree RD140/2003 bears in thoughts the usage of different merchandise but even so chlorine. Chlorine is extensively used because of its top availability and its low price, nevertheless it has a chain of disadvantages, as it will increase the water pH boosting precipitations, and it interferes with the great solubility of a few medication (every so often it’s recommendable to not chlorinate water all through the remedies with antibiotics). The behaviour of the chlorine towards the biofilm is unsure and its spectrum is incomplete. This present day different merchandise are considered with the intention to sanitize the water, and their options are evaluated within the following desk.


Desk 2. Options of water sanitizers. Supply: CEVA Salud Animal.













Stabilized peroxides Chlorinated compounds Natural acids Iodized compounds
Spectrum +++ ++ ++ ++
Corrosion of fabrics + + +
Toxicity + + +
Irritant ++ ++ +
Damaging motion on rubbers and plastics ++
Efficacy towards natural subject +++ + +
Velocity of motion +++ ++ ++ ++
Favoring of biofilm + + +


We will be able to additionally believe ozone, UV gentle, or filtration that have a significantly better efficacy, however their price is upper. Hydrogen peroxide (H2O2) is gaining in recognition as a sanitizer and it has very fascinating options (see desk).


3.2. Sanitizing by way of the dosing pump:


It’s not recommendable to make use of drug dispensers, as a result of they paintings at an overly top dosing point and this obliges us to make very top and steady dilutions. Additionally, the sanitizers can hurt their membranes.


The water sanitizer dosing pumps are electric gadgets that inject a certain quantity of liquid within a pipe or a tank, and we will be able to regulate them. They paintings at the foundation of a nominal go with the flow charge (most %) and at a undeniable force. The most typical ones paintings at a most go with the flow charge of three liters/hour and at a force of seven bars. There are two primary sorts:


  • Consistent dosing: Nominal go with the flow charge (0%-100%). We will have to know the water go with the flow charge (liters/hour) to be handled with the intention to regulate it. Its working is computerized and we now have the opportunity of putting in place a timer.
  • Proportional dosing: Go with the flow charge proportional to the sign facilitated by way of a meter that emits pulses, injecting handiest in line with the go with the flow charge that circulates during the pipe. The program is a lot more exact.


Figure 7. Sanitation system. Left: Chlorine dosing pump, Center: Hydrogen peroxide dosing pump, Right: Filter, flow rate meter and "by pass".
Determine 7. Sanitation gadget. Left: Chlorine dosing pump, Heart: Hydrogen peroxide dosing pump, Proper: Clear out, go with the flow charge meter and “by way of move”.

The injection level will have to be situated within the phase of the pipe situated between the influent level and the overall garage tank.


4. The significance of keeping up all the drugs gadget blank


A find out about tested the publicity of water-soluble medication to different merchandise (pH modifiers, acids, and others) most often administered during the water. The result of this find out about underline the significance of keeping up all the drug administering gadget (tanks, dispensers, pipes, and many others.) blank. As an example, the addition of citric acid and ammonia for the amendment of the pH brought about reactions and residues in 9 out of the 15 medication that had been evaluated.

Figure 8. pH range of different drugs in the water and % reaction with the other compounds. Source: Dorr PM, Madson M, Wayne S, et al. (2009).
Determine 8. pH vary of various medication within the water and % response with the opposite compounds. Supply: Dorr PM, Madson M, Wayne S, et al. (2009).


Because of this, when ingredients are injected within the pipes with the purpose of cleansing and disinfecting them as, as an example, sodium hypoclorite, the practical motion is to scrub with “contemporary water” (“Flushing”) earlier than administering any water-soluble healing product. If we don’t do it, residues can also be produced and so they may just block the dispensers, pipes and drinkers.

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